Struggling with dry, dull, or crepey skin in your 40s? At Epitomi Aesthetics in Epsom, we offer Profhilo treatment — a gentle injectable that stimulates collagen and elastin, hydrates from within, and helps restore your skin’s natural glow. Especially effective for perimenopausal skin, Profhilo supports long-term skin health without altering your features.
Turning 40 often brings skin changes due to hormonal shifts, particularly during perimenopause. Common issues include loss of glow, dryness, and sagging linked to decreased collagen and estrogen levels. Profhilo is a gentle, regenerative solution for those hesitant about traditional fillers.
Why Your Skin Changes from your 30s onwards, with marked changes during Perimenopause
According to the NHS.co.uk menopausal symptoms often include changes to skin texture and sensitivity. Many women also experience unexpected breakouts, redness, or itchiness – which can feel both unfamiliar and frustrating. I see this every week in my GP practice with the female patients who I review.
- Hormonal changes in the 40s and 50s lead to reduced collagen and elastin production.
- Symptoms include loss of hydration, skin elasticity, increased fine lines, and volume loss.
- Many women experience unexpected skin issues like breakouts and sensitivity during this time.
How Profhilo Works Beneath the Skin

- Profhilo is a bio-remodelling injection made of high concentrations of hyaluronic acid (HA).
- It improves skin quality by boosting HA levels and stimulating collagen and elastin production.
- The treatment enhances hydration and firmness without adding volume.
Why Profhilo Is Ideal for Perimenopausal Skin
- Benefits include smoothing fine lines, increased hydration, and improved skin texture.
- It retains moisture, stimulates collagen production, and offers natural-looking results.
- Patients often seek a fresher appearance rather than looking younger.
What to Expect From Profhilo Treatment in Epsom
Treatment typically involves two sessions, four weeks apart, with top-ups every 6-9 months. Most patients report little discomfort and mild swelling post-treatment. Results build gradually over 4-6 weeks, with maximum effects at 8 weeks.
How long does it take for Profhilo to work?
- HA molecules begin drawing in water within 48 hours, enhancing skin hydration.
- Collagen and elastin production increases over the following weeks.
- If maintenance is not kept, skin may revert to previous conditions over time.
What is the downtime after Profhilo?
- Small lumps may appear at injection sites but will disperse within 24-48 hours.
- Patients can return to normal activities immediately, but bruising may occur.
Is Profhilo painful?
- The treatment is mildly uncomfortable, with some patients using numbing cream.
- Most tolerate the procedure well and return for follow up appointments
What happens in a Profhilo treatment?
- A consultation is conducted to assess suitability and discuss concerns.
- The treatment involves multiple shallow injections, taking about 10 minutes.
- Patients are scheduled for a booster treatment after four weeks.
What are the risks and side effects of Profhilo?
- Main risks include bruising and mild swelling at injection sites.
- Infection risk is low due to sterile techniques, and allergic reactions are rare.
Real Patient Story
Helen, a 47-year-old teacher from Epsom, shared her positive experience, of her natural-looking results from Profhilo:
” Profhilo felt like skincare that actually worked. Within a month, people started telling me I looked well. That was exactly what I wanted.”
Profhilo vs Fillers: Which Is Right for You?
- Profhilo focuses on improving skin quality, while fillers add volume.
- It is ideal for those seeking subtle improvements without altering facial features.
- A combination of treatments may be recommended based on individual needs.
Feature | Profhilo | Dermal Fillers |
---|---|---|
Primary Purpose | Improves overall skin quality | Adds volume and structure to specific areas |
Main Ingredient | Pure hyaluronic acid (HA) | Cross-linked hyaluronic acid or other volumising agents |
Results | Smoother, firmer, more hydrated skin | Lifted, contoured facial features |
Treatment Areas | Whole face, neck, décolletage, hands | Cheeks, lips, chin, jawline, nasolabial folds |
Effect on Facial Shape | No added volume – maintains natural features | Adds volume – can reshape facial contours |
Best For | Subtle rejuvenation and skin refresh | Volume loss, definition, and contouring |
Ideal Candidate | Those seeking natural improvement without looking ‘done’ | Those wanting visible enhancements or correction |
Conclusion: It’s Not About Looking Younger – It’s About Feeling Like You Again
Profhilo helps restore skin affected by hormonal changes, promoting confidence and a fresh appearance.
How much does Profhilo cost?
The cost is £325 for a single treatment or £600 for two treatments. Consultations are available for those interested in the treatment.
Profhilo Treatment FAQ’s
Is Profhilo painful?
Profhilo is generally comfortable with mild discomfort, with numbing cream available.
Is Profhilo right for me if I want natural results?
It is suitable for those seeking natural results without altering facial features.
Can Profhilo help with crepey skin on the neck and jawline?
Profhilo effectively treats crepey skin on the neck and jawline
How long does Profhilo last?
Results typically last 6-9 months, with maintenance treatments recommended biannually.

Dr Effie
Dr. Effie is a highly skilled and experienced Medical Aesthetics Doctor, General Practitioner, and the proud owner of Epitomi Aesthetics. In an industry that remains largely unregulated, Dr. Effie is deeply committed to raising standards and ensuring patient safety. She consistently invests in professional excellence, holding several postgraduate qualifications and completing advanced masters level training.